| Gran Teatre del Liceu | | | |
| Massimo Zanetti | Conductor | | |
| José Luis Gómez | Director | | |
| Carl Fillion | Set Designer | | |
| Alejandro Andújar | Costume Designer | | |
| Coro del Gran Teatre del Liceu | | | |
| Orquesta Sinfónica del Gran Teatre del Liceu | | | |
| Leo Nucci | Baritone | Simon Boccanegra | 2016 Apr 12, 17 |
| Giovanni Meoni | Baritone | Simon Boccanegra | 2016 Apr 22, 25, 28 |
| Plácido Domingo | Tenor | Simon Boccanegra | 2016 Apr 23, 26, 29 |
| Ildebrando D'Arcangelo | Baritone | Jacopo Fiesco | 2016 Apr 12, 17, 22, 25, 28 |
| Ferruccio Furlanetto | Bass | Jacopo Fiesco | 2016 Apr 23, 26, 29 |
| Barbara Frittoli | Soprano | Amelia Grimaldi (Maria Boccanegra) | 2016 Apr 12, 17, 22, 25, 28 |
| Davinia Rodríguez | Soprano | Amelia Grimaldi (Maria Boccanegra) | 2016 Apr 23, 26, 29 |
| Fabio Sartori | Tenor | Gabriele Adorno | 2016 Apr 12, 17, 22, 25, 28 |
| Ramón Vargas | Tenor | Gabriele Adorno | 2016 Apr 23, 26, 29 |
| Ángel Ódena | Baritone | Paolo Albiani | 2016 Apr 12, 17, 22, 25, 28 |
| Elia Fabbian | Bass | Paolo Albiani | 2016 Apr 23, 26, 29 |
| Damián del Castillo | Baritone | Pietro | |