| The Royal Opera | | | |
| Sir Antonio Pappano | Conductor | | 2017 Nov 19 mat, 22, 25, 28, Dec 04, 08 |
| Christopher Willis | Conductor | | 2017 Dec 13, 16 |
| David Alden | Director | | |
| Paul Steinberg | Set Designer | | |
| Buki Shiff | Costume Designer | | |
| Royal Opera Chorus | | | |
| Orchestra of the Royal Opera House Covent Garden | | | |
| Joyce DiDonato | Mezzo-soprano | Semiramide | |
| Bálint Szabó | Bass | Oroe | |
| Michele Pertusi | Baritone | Assur | 2017 Nov 19 mat, 22, 25, 28, Dec 04, 08, 13 |
| Mirco Palazzi | Bass | Assur | 2017 Nov 19 mat, Dec 16 |
| Lawrence Brownlee | Tenor | Idreno | |
| Daniela Barcellona | Mezzo-soprano | Arsace | |
| Jacquelyn Stucker | Mezzo-soprano | Azema | |
| Konu Kim | Tenor | Mitrane | |
| Simon Shibambu | Bass | Nino's ghost | |