| San Francisco Opera | ||
| Karen Kamensek | Conductor | |
| John Fulljames | Director | |
| Chloe Lamford | Set Designer | |
| Christina Cunningham | Costume Designer | |
| Fabiana Piccioli | Lighting Designer | |
| San Francisco Opera Orchestra | ||
| San Francisco Opera Chorus | ||
| Lucy Bradley | Director | |
| John Keene | Choirmaster / chorus director | |
| Irene Roberts | Mezzo-soprano | Offred |
| Simone McIntosh | Soprano | The Double |
| Christopher Oglesby | Tenor | Luke |
| Gabrielle Beteag | Mezzo-soprano | Offred's mother |
| Sarah Cambidge | Soprano | Aunt Lydia |
| Katrina Galka | Soprano | Janine/Ofwarren |
| Lindsay Ammann | Contralto | Serena Joy |
| Sara Couden | Mezzo-soprano | Rita |
| John Relyea | Bass-baritone | The Commander |
| Brenton Ryan | Tenor | Nick |
| Matthew Dibattista | Tenor | The Doctor |