| Metropolitan Opera | | | |
| Carlo Rizzi | Conductor | | |
| Sir David McVicar | Director | | |
| Charles Edwards | Set Designer | | |
| Brigitte Reiffenstuel | Costume Designer | | |
| Adam Silverman | Lighting Designer | | |
| The Metropolitan Opera Orchestra | | | |
| The Metropolitan Opera Chorus | | | |
| Günther Groissböck | Bass | Filippo II | |
| Russell Thomas | Tenor | Don Carlo | 2022 Nov 03, 11, 15, 19 mat, 23, 26, Dec 03 mat |
| Rafael Davila | Tenor | Don Carlo | 2022 Nov 07, 30 |
| Peter Mattei | Baritone | Rodrigo, Marchese di Posa | |
| John Relyea | Bass-baritone | Il Grande Inquisitore | |
| Eleonora Buratto | Soprano | Elisabetta di Valois | 2022 Nov 03, 07, 11, 15, 19 mat |
| Angela Meade | Soprano | Elisabetta di Valois | 2022 Nov 23, 26, 30, Dec 03 mat |
| Yulia Matochkina | Mezzo-soprano | La Principessa Eboli | |
| Alexandros Stavrakakis | Bass | Un frate | |